Compile Data Set for Download or QSAR
Found 308 of ki data for polymerid = 50000110,50002570,50003332
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50526264(CHEMBL4452694)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272J5PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50526265(CHEMBL4520656)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272J5PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50591808(CHEMBL5207397)copy SMILES
Affinity DataKi:  4.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2FM0PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50563999(CHEMBL4595698)copy SMILES
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]NO711 from mouse GAT1 expressed in HEK293 cells measured after 40 mins of incubation by LC-ESI-MS-MS methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2MJJPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50526262(CHEMBL4439989)copy SMILEScopy InChI
Affinity DataKi:  5.10nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272J5PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50526260(CHEMBL4554639)copy SMILEScopy InChI
Affinity DataKi:  5.90nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272J5PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50526261(CHEMBL4565664)copy SMILEScopy InChI
Affinity DataKi:  5.90nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272J5PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50505281(CHEMBL2315948)copy SMILEScopy InChI
Affinity DataKi:  8.10nMAssay Description:Inhibition of NO711 binding to mouse GAT1 receptor expressed in HEK293 cell membranes incubated for 1 hr by LC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WFXPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50591807(CHEMBL5178760)copy SMILES
Affinity DataKi:  8.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2FM0PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50526259(CHEMBL4565745)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272J5PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50526258(CHEMBL4455995)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272J5PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080367((R)-1-{2-[(Z)-2-(2-Chloro-phenyl)-2-phenyl-vinylox...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50526257(CHEMBL4555282)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272J5PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080358(1-{2-[2,2-Bis-(2-chloro-phenyl)-vinyloxy]-ethyl}-1...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080382((R)-1-{2-[(Z)-2-(2-Chloro-phenyl)-2-o-tolyl-vinylo...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50591806(CHEMBL5205864)copy SMILES
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2FM0PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50526263(CHEMBL4475547)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272J5PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080337((R)-1-{2-[2,2-Bis-(3-methyl-thiophen-2-yl)-vinylox...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50334247((R,E)-1-(4-(2-fluorophenyl)-4-o-tolylbut-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  14.8nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153W6PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  17.0nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50526256(CHEMBL4551183)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272J5PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080376((R)-1-{2-[(E)-2-(3-Methyl-thiophen-2-yl)-2-o-tolyl...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50417649(CHEMBL1642396)copy SMILEScopy InChI
Affinity DataKi:  18.2nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153W6PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080327(1-{2-[(Z)-2-(2-Fluoro-phenyl)-2-o-tolyl-vinyloxy]-...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080335((R)-1-[2-(2,2-Di-o-tolyl-vinyloxy)-ethyl]-piperidi...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50417641(CHEMBL1642400)copy SMILEScopy InChI
Affinity DataKi:  19.1nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153W6PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50417627(CHEMBL1642378)copy SMILEScopy InChI
Affinity DataKi:  20.4nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153W6PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080375((R)-1-[2-((E)-2-Phenyl-2-o-tolyl-vinyloxy)-ethyl]-...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50417639(CHEMBL1642397)copy SMILEScopy InChI
Affinity DataKi:  21.9nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153W6PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080368(1-[2-(2,2-Di-o-tolyl-vinyloxy)-ethyl]-1,2,5,6-tetr...)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080388((R)-1-{2-[(E)-2-(3-Fluoro-phenyl)-2-o-tolyl-vinylo...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as residual binding preincubated for 4 hrs followed by NO711 ad...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50417626(CHEMBL1642376)copy SMILEScopy InChI
Affinity DataKi:  28.8nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153W6PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50417628(CHEMBL1642379)copy SMILEScopy InChI
Affinity DataKi:  29.5nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153W6PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080331((R)-1-{2-[(Z)-2-(4-Fluoro-2-methyl-phenyl)-2-o-tol...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50466795(CHEMBL4292451)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Displacement of NO711 from mouse GAT1 expressed in stable HEK293 cells preincubated for 10 mins followed by NO711 addition and measured after 40 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7CSGPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080355((R)-1-{2-[2,2-Bis-(2-ethyl-phenyl)-vinyloxy]-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080365((R)-1-{2-[1-(2,4-Dichloro-phenyl)-1-(3-methyl-thio...)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50417631(CHEMBL1642384)copy SMILEScopy InChI
Affinity DataKi:  33.9nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153W6PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Displacement of NO711 from mouse GAT1 expressed in stable HEK293 cell membranes preincubated for 10 mins followed by NO711 addition and measured afte...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Binding affinity to mouse GAT1 expressed in HEK293 cells using NO71156 as unlabelled marker by LC-ESI-MS-MS based competitive MS binding assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Displacement of NO 711 from mouse GAT1 expressed in HEK293 cell membranes after 40 mins by LC-ESI-MS-MS-based MS binding assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Inhibition of NO711 binding to mouse GAT1 expressed in HEK293 cell membranes assessed as reduction in NO711 binding at incubated for 4 hrs in presenc...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Displacement of NO711 from mouse GAT1 expressed in stable HEK293 cell membranes preincubated for 10 mins followed by NO711 addition and measured afte...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  37nMMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Inhibition of [2H10]NO 711 binding to mouse GAT1 expressed in HEK293 cell membranes by mass spectrometric analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50417638(CHEMBL1642395)copy SMILEScopy InChI
Affinity DataKi:  38.0nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153W6PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50417642(CHEMBL1642401)copy SMILEScopy InChI
Affinity DataKi:  38.9nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153W6PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)copy SMILEScopy InChI
Affinity DataKi:  39nMAssay Description:Binding affinity to mouse GAT1 stably transfected in HEK293 cells by NO-711 binding assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£nchen

Curated by ChEMBL
LigandPNGBDBM50080328((R)-1-{2-[Bis-(2-chloro-phenyl)-methyleneaminooxy]...)copy SMILEScopy InChI
Affinity DataKi:  39nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GMVPubMed
Displayed 1 to 50 (of 308 total ) | Next | Last >>
Jump to: